Ghrelin, the endogenous ligand for the growth hormone (GH) secretagogue (GHS) receptor, is secreted by the stomach and circulates in the blood at measurable concentrations. Ghrelin regulates GH release and plays a role in the regulation of food intake (FI) and energy balance. In parallel [...]
Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. T hey have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals [...]
Older muscles function and perform less well than young muscles, and that is partly because older muscles convert nutrients into energy less effectively. In older muscle cells the mitochondria, the power plants of the cell, work less well. According to an animal study, that Italian [...]
The aging process makes the heart muscle become stiffer, and the amount of oxygen-rich blood that the left ventricle of the heart muscle can pump into the body decreases. The possible end result? Heart failure, a a medical condition in which the body languishes due [...]
There may be a medicine that helps obese people to lose excess weight effectively. No, it's not an obscure high-tech drug with an unpronounceable name that does interesting things to lab rats. According to researchers at the University of Sydney in Australia, the ancient D-amphetamine [...]
If you eat 150 grams of fresh oyster mushrooms every day, your sensitivity to insulin increases and the amount of triglycerides and 'bad cholesterol' in your blood decreases. Nutritional scientists from the Birdem hospital in Dhaka, the capital of Bangladesh, discovered this. Study The researchers [...]
SARMs are the successors of the good, old anabolic steroids. A number of these, such as RAD140 and LGD4033, have already become established in pharmacological bodybuilding. GlaxoSmithKline (GSK) researchers are researching another SARM, about which they release remarkably little. But what we have learned about [...]
A low-calorie diet drives testosterone production down, a real nuisance for natural athletes who not only want to decimate their fat reserves but also maintain their lean body mass. Supplementing with capsaicin – and perhaps analogues too – may offer hope, according to a Turkish [...]
According to biotechnologists at National Chung Hsing University in Taiwan, Ching-Shin Oolong tea contains phenols that boost the secretion of growth hormone. In-vitro and animal studies have shown that these compounds activate the receptor for the hunger hormone ghrelin. Chin-Shin Oolong Tea Chin-Shin Oolong Tea [...]
It would of course be expensive, but in theory there's a lot to be said for combining growth hormone and IGF-1, writes the Dutch endocrinologist Joop Janssen in an article in Reviews in Endocrine Metabolic Disorders. The article is worth looking at if you're a [...]
